Glycogen Metabolism in Glycogen-rich Erythrocytes

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Glycogen metabolism in glycogen-rich erythrocytes.

High concentrations of red blood cell glycogen were visualized by el.ctron microscopy and demonstrated biochemically in amylo1 ,6-glucosidaseand phosphorylase-deficient red blood cells. Glycogen concentration decreased as a function of cell age. Similar incorporation rates of ‘4C-U-glucose into glycogen were observed in amylo-1 ,6-glucosidase-deflcient and normal erythrocytes, characterized by ...

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In the human body, glycogen is a branched polymer of glucose stored mainly in the liver and the skeletal muscle that supplies glucose to the blood stream during fasting periods and to the muscle cells during muscle contraction. Glycogen has been identified in other tissues such as brain, heart, kidney, adipose tissue, and erythrocytes, but glycogen function in these tissues is mostly unknown. G...

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ژورنال

عنوان ژورنال: Blood

سال: 1974

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v44.2.275.275